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AAVrh.10-Mediated Expression of an Anti-Cocaine Antibody Mediates Persistent Passive Immunization That Suppresses Cocaine-Induced Behavior

Cocaine addiction is a major problem affecting all societal and economic classes for which there is no effective therapy. We hypothesized an effective anti-cocaine vaccine could be developed by using an adeno-associated virus (AAV) gene transfer vector as the delivery vehicle to persistently express...

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Detalhes bibliográficos
Main Authors: Rosenberg, Jonathan B., Hicks, Martin J., De, Bishnu P., Pagovich, Odelya, Frenk, Esther, Janda, Kim D., Wee, Sunmee, Koob, George F., Hackett, Neil R., Kaminsky, Stephen M., Worgall, Stefan, Tignor, Nicole, Mezey, Jason G., Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360503/
https://ncbi.nlm.nih.gov/pubmed/22486244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.178
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