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AAV-directed Persistent Expression of an Anti-nicotine Antibody Gene for Smoking Cessation

Current strategies to help tobacco smokers quit have limited success as a result of the addictive properties of the nicotine in cigarette smoke. We hypothesized that a single administration of an adeno-associated virus (AAV) gene transfer vector expressing high levels of an anti-nicotine antibody wo...

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Detalhes bibliográficos
Main Authors: Hicks, Martin J., Rosenberg, John B., De, Bishnu P., Pagovich, Odelya, Young, Colin N., Qiu, Jian-ping, Kaminsky, Stephen M., Hackett, Neil R., Worgall, Stefan, Janda, Kim D., Davisson, Robin L., Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622954/
https://ncbi.nlm.nih.gov/pubmed/22745437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003611
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