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17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

Rationale: 17β-Estradiol (E2) attenuates hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension (HPH) through an unknown mechanism that may involve estrogen receptors (ER) or E2 conversion to catecholestradiols and methoxyestradiols with previously unrecognized effects on cardiopulmon...

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Detalhes bibliográficos
Main Authors: Lahm, Tim, Albrecht, Marjorie, Fisher, Amanda J., Selej, Mona, Patel, Neel G., Brown, Jordan A., Justice, Matthew J., Brown, M. Beth, Van Demark, Mary, Trulock, Kevin M., Dieudonne, Dino, Reddy, Jagadeshwar G., Presson, Robert G., Petrache, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359941/
https://ncbi.nlm.nih.gov/pubmed/22383500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201107-1293OC
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