17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

Rationale: 17β-Estradiol (E2) attenuates hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension (HPH) through an unknown mechanism that may involve estrogen receptors (ER) or E2 conversion to catecholestradiols and methoxyestradiols with previously unrecognized effects on cardiopulmon...

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Main Authors: Lahm, Tim, Albrecht, Marjorie, Fisher, Amanda J., Selej, Mona, Patel, Neel G., Brown, Jordan A., Justice, Matthew J., Brown, M. Beth, Van Demark, Mary, Trulock, Kevin M., Dieudonne, Dino, Reddy, Jagadeshwar G., Presson, Robert G., Petrache, Irina
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2012
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359941/
https://ncbi.nlm.nih.gov/pubmed/22383500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201107-1293OC
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