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2251: An estrogen receptor α (ERα)-BMPR2-apelin axis mediates 17β-estradiol’s protective effects on right ventricular function in experimental pulmonary hypertension (PH)
OBJECTIVES/SPECIFIC AIMS: Women with pulmonary arterial hypertension (PAH) exhibit superior right ventricular (RV) function and survival compared with men, a phenomenon attributed to poorly understood cardioprotective effects of 17β-estradiol (E2). We hypothesize that E2, through ERα, attenuates PH-...
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| 出版年: | J Clin Transl Sci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cambridge University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6804580/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.214 |
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