Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects of endogenous and exogenous sex hormones

Estrogens are disease modifiers in PAH. Even though female patients exhibit better right ventricular (RV) function than men, estrogen effects on RV function (a major determinant of survival in PAH) are incompletely characterized. We sought to determine whether sex differences exist in RV function in...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Frump, Andrea L., Goss, Kara N., Vayl, Alexandra, Albrecht, Marjorie, Fisher, Amanda, Tursunova, Roziya, Fierst, John, Whitson, Jordan, Cucci, Anthony R., Brown, M. Beth, Lahm, Tim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421786/
https://ncbi.nlm.nih.gov/pubmed/25713318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00006.2015
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