17β-Estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension

17β-Estradiol (E(2)) exerts protective effects on right ventricular (RV) function in pulmonary arterial hypertension (PAH). Since acute exercise-induced increases in afterload may lead to RV dysfunction in PAH, we sought to determine whether E(2) allows for superior RV adaptation after an acute exer...

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Publié dans:Am J Physiol Lung Cell Mol Physiol
Auteurs principaux: Lahm, Tim, Frump, Andrea L., Albrecht, Marjorie E., Fisher, Amanda J., Cook, Todd G., Jones, Thomas J., Yakubov, Bakhtiyor, Whitson, Jordan, Fuchs, Robyn K., Liu, Aiping, Chesler, Naomi C., Brown, M. Beth
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142461/
https://ncbi.nlm.nih.gov/pubmed/27288487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00132.2016
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