Neonatal hyperoxic lung injury favorably alters adult right ventricular remodeling response to chronic hypoxia exposure

The development of pulmonary hypertension (PH) requires multiple pulmonary vascular insults, yet the role of early oxygen therapy as an initial pulmonary vascular insult remains poorly defined. Here, we employ a two-hit model of PH, utilizing postnatal hyperoxia followed by adult hypoxia exposure, t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Goss, Kara N., Cucci, Anthony R., Fisher, Amanda J., Albrecht, Marjorie, Frump, Andrea, Tursunova, Roziya, Gao, Yong, Brown, Mary Beth, Petrache, Irina, Tepper, Robert S., Ahlfeld, Shawn K., Lahm, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398870/
https://ncbi.nlm.nih.gov/pubmed/25659904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00276.2014
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