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Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS

The compositional and conformational changes during catalytic activation of the spliceosome promoted by the DEAH box ATPase Prp2 are only poorly understood. Here, we show by dual-color fluorescence cross-correlation spectroscopy (dcFCCS) that the binding affinity of several proteins is significantly...

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Main Authors: Ohrt, Thomas, Prior, Mira, Dannenberg, Julia, Odenwälder, Peter, Dybkov, Olexandr, Rasche, Nicolas, Schmitzová, Jana, Gregor, Ingo, Fabrizio, Patrizia, Enderlein, Jörg, Lührmann, Reinhard
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358646/
https://ncbi.nlm.nih.gov/pubmed/22535589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.033316.112
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