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Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system
Step 2 catalysis of pre-mRNA splicing entails the excision of the intron and ligation of the 5′ and 3′ exons. The tasks of the splicing factors Prp16, Slu7, Prp18, and Prp22 in the formation of the step 2 active site of the spliceosome and in exon ligation, and the timing of their recruitment, remai...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683925/ https://ncbi.nlm.nih.gov/pubmed/23685439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039024.113 |
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