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Reductively-responsive siRNA-conjugated hydrogel nanoparticles for gene silencing
A critical need still remains for effective delivery of RNA interference (RNAi) therapeutics to target tissues and cells. Self-assembled lipid- and polymer-based systems have been most extensively explored for transfection with small interfering RNA (siRNA) in liver and cancer therapies. Safety and...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357068/ https://ncbi.nlm.nih.gov/pubmed/22475061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja300174v |
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