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Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing

Gene silencing mediated by small interfering RNA (siRNA) is a novel approach in the development of new cancer therapeutics. Polycations used for nucleic acid delivery still remain heterogeneous compounds, despite continuous progress in polymer synthetic technologies. Here we report the development o...

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書誌詳細
主要な著者: Dohmen, Christian, Fröhlich, Thomas, Lächelt, Ulrich, Röhl, Ingo, Vornlocher, Hans-Peter, Hadwiger, Philipp, Wagner, Ernst
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381594/
https://ncbi.nlm.nih.gov/pubmed/23344624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2011.10
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