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Chitosan Hydrogel as siRNA vector for prolonged gene silencing

BACKGROUND: The periodontitis is one of the most prevalent diseases with alveolar resorption in adult people and is the main cause of the tooth loss. To investigate the possibility for protecting the loss of alveolar bone in periodontal diseases, a RNAi-based therapeutic strategy is applied for sile...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ma, Zhiwei, Yang, Chuanxu, Song, Wen, Wang, Qintao, Kjems, Jørgen, Gao, Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104730/
https://ncbi.nlm.nih.gov/pubmed/24946934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-12-23
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