Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion

Titanium surface modification is crucial to improving its bioactivity, mainly its bone binding ability in bone implant materials. In order to functionalize titanium with small interfering RNA (siRNA) for sustained gene silencing in nearby cells, the layer-by-layer (LbL) approach was applied using so...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Song, Wen, Song, Xin, Yang, Chuanxu, Gao, Shan, Klausen, Lasse Hyldgaard, Zhang, Yumei, Dong, Mingdong, Kjems, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378287/
https://ncbi.nlm.nih.gov/pubmed/25848254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S76513
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