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Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
Harnessing the RNA interference pathway offers a new therapeutic modality; however, solutions to overcome biological barriers to small interfering RNA (siRNA) delivery are required for clinical translation. This work demonstrates, by direct northern and quantitative PCR (qPCR) detection, stability,...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4098703/ https://ncbi.nlm.nih.gov/pubmed/23462963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.2 |
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