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Direct Force Measurements between siRNA and Chitosan Molecules Using Force Spectroscopy

Information on the interaction strength between small interfering RNA (siRNA) and chitosan can contribute to the understanding of the formation and stability of chitosan/siRNA nanoparticles used as siRNA delivery systems for gene silencing. In this study, we utilize atomic force microscopy to obtain...

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Detalhes bibliográficos
Main Authors: Xu, Sailong, Dong, Mingdong, Liu, Xiudong, Howard, Kenneth A., Kjems, Jørgen, Besenbacher, Flemming
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913138/
https://ncbi.nlm.nih.gov/pubmed/17483179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.093229
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