Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing

Small interfering RNA (siRNA) has found many applications in tissue regeneration and disease therapeutics. Effective and localized siRNA delivery remains challenging, reducing its therapeutic potential. Here, we report a strategy to control and prolong siRNA release by directly tethering transfectio...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Nguyen, Minh Khanh, Huynh, Cong Truc, Gilewski, Alex, Wilner, Samantha E., Maier, Keith E., Kwon, Nicholas, Levy, Mathew, Alsberg, Eben
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713499/
https://ncbi.nlm.nih.gov/pubmed/31489374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax0801
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados