Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing

Small interfering RNA (siRNA) has found many applications in tissue regeneration and disease therapeutics. Effective and localized siRNA delivery remains challenging, reducing its therapeutic potential. Here, we report a strategy to control and prolong siRNA release by directly tethering transfectio...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Nguyen, Minh Khanh, Huynh, Cong Truc, Gilewski, Alex, Wilner, Samantha E., Maier, Keith E., Kwon, Nicholas, Levy, Mathew, Alsberg, Eben
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713499/
https://ncbi.nlm.nih.gov/pubmed/31489374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax0801
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars