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Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo

To achieve the great potential of siRNA based gene therapy, safe and efficient systemic delivery in vivo is essential. Here we report reductively responsive hydrogel nanoparticles with highly uniform size and shape for systemic siRNA delivery in vivo. “Blank” hydrogel nanoparticles with high aspect...

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Detaylı Bibliyografya
Yayımlandı:Mol Pharm
Asıl Yazarlar: Ma, Da, Tian, Shaomin, Baryza, Jeremy, Luft, J. Christopher, DeSimone, Joseph M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839470/
https://ncbi.nlm.nih.gov/pubmed/26287725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00054
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