More Effective Nanomedicines through Particle Design

Por Wang, Jin, Byrne, James D., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2011

Engineering nanomedicines using stimuli-responsive biomaterials

Por Wang, Yapei, Byrne, James D., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2012

PRINT: A Novel Platform Toward Shape and Size Specific Nanoparticle Theranostics

Por PERRY, JILLIAN L., HERLIHY, KEVIN P., NAPIER, MARY E., DESIMONE, JOSEPH M.
Publicado em 2011

Potent Engineered PLGA Nanoparticles by Virtue of Exceptionally High Chemotherapeutic Loadings

Por Enlow, Elizabeth M., Luft, J. Christopher, Napier, Mary E., DeSimone, Joseph M.
Publicado em 2011

The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies

Por Wang, Jin, Tian, Shaomin, Petros, Robby A., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2010

Microfabricated Particles for Engineered Drug Therapies: Elucidation into the Mechanisms of Cellular Internalization of PRINT Particles

Por Gratton, Stephanie E. A., Napier, Mary E., Ropp, Patricia A., Tian, Shaomin, DeSimone, Joseph M.
Publicado em 2008

The Effect of Aspect Ratio and Deformability on Nanoparticle Extravasation through Nanopores

Por Kersey, Farrell R., Merkel, Timothy J., Perry, Jillian L., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2012

Tunable Bifunctional Silyl Ether Cross-Linkers for the Design of Acid Sensitive Biomaterials

Por Parrott, Matthew C., Luft, J. Chris, Byrne, James D., Fain, John H., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2010

Incorporation and Controlled Release of Silyl Ether Prodrugs from PRINT Nanoparticles

Por Parrott, Matthew C., Finniss, Mathew, Luft, J. Chris, Pandya, Ashish, Gullapalli, Anuradha, Napier, Mary E., DeSimone, Joseph M.
Publicado em 2012

Low Modulus Biomimetic Microgel Particles with High Loading of Hemoglobin

Por Chen, Kai, Merkel, Timothy J., Pandya, Ashish, Napier, Mary E., Luft, J. Christopher, Daniel, Will, Sheiko, Sergei, DeSimone, Joseph M.
Publicado em 2012

The effect of particle design on cellular internalization pathways

Por Gratton, Stephanie E. A., Ropp, Patricia A., Pohlhaus, Patrick D., Luft, J. Christopher, Madden, Victoria J., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2008

The Effect of Particle Size on the Biodistribution of Low-modulus Hydrogel PRINT Particles

Por Merkel, Timothy J., Chen, Kai, Jones, Stephen W., Pandya, Ashish A., Tian, Shaomin, Napier, Mary E., Zamboni, William E., DeSimone, Joseph M.
Publicado em 2012

Reductively-responsive siRNA-conjugated hydrogel nanoparticles for gene silencing

Por Dunn, Stuart S., Tian, Shaomin, Blake, Steven, Wang, Jin, Galloway, Ashley L., Murphy, Andrew, Pohlhaus, Patrick D., Rolland, Jason P., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2012

RNA Replicon Delivery via Lipid-Complexed PRINT Protein Particles

Por Xu, Jing, Luft, J. Christopher, Yi, Xianwen, Tian, Shaomin, Owens, Gary, Wang, Jin, Johnson, Ashley, Berglund, Peter, Smith, Jonathan, Napier, Mary E., DeSimone, Joseph M.
Publicado em 2013

Folate-targeted Polymeric Nanoparticle Formulation of Docetaxel is an Effective Molecularly Targeted Radiosensitizer with Efficacy Dependent on the Timing of Radiotherapy

Por Werner, Michael E., Copp, Jonathan A., Karve, Shrirang, Cummings, Natalie D., Sukumar, Rohit, Li, Chenxi, Napier, Mary E., Chen, Ronald C., Cox, Adrienne D., Wang, Andrew Z.
Publicado em 2011

Rendering Protein-Based Particles Transiently Insoluble for Therapeutic Applications

Por Xu, Jing, Wang, Jin, Luft, J. Christopher, Tian, Shaomin, Owens, Gary, Pandya, Ashish A., Berglund, Peter, Pohlhaus, Patrick, Maynor, Benjamin W., Napier, Mary E., DeSimone, Joseph M.
Publicado em 2012

The Pursuit of a Scalable Nanofabrication Platform for Use in Material and Life Science Applications

Por GRATTON, STEPHANIE E. A., WILLIAMS, STUART S., NAPIER, MARY E., POHLHAUS, PATRICK D., ZHOU, ZHILIAN, WILES, KENTON B., MAYNOR, BENJAMIN W., SHEN, CLIFTON, OLAFSEN, TOVE, SAMULSKI, EDWARD T., DESIMONE, JOSEPH M.
Publicado em 2008

Delivery of Multiple siRNAs Using Lipid-coated PLGA Nanoparticles for Treatment of Prostate Cancer

Por Hasan, Warefta, Chu, Kevin, Gullapalli, Anuradha, Dunn, Stuart S., Enlow, Elizabeth M., Luft, J. Christopher, Tian, Shaomin, Napier, Mary E., Pohlhaus, Patrick D., Rolland, Jason P., DeSimone, Joseph M.
Publicado em 2011

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft

Por Chu, Kevin S., Hasan, Warefta, Rawal, Sumit, Walsh, Mark D., Enlow, Elizabeth M., Luft, J. Christopher, Bridges, Arlene S., Kuijer, Jennifer L., Napier, Mary E., Zamboni, William C., DeSimone, Joseph M.
Publicado em 2012

Particle Replication in Nonwetting Templates Nanoparticles with Tumor Selective Alkyl Silyl Ether Docetaxel Prodrug Reduces Toxicity

Por Chu, Kevin S., Finniss, Mathew C., Schorzman, Allison N., Kuijer, Jennifer L., Luft, J. Christopher, Bowerman, Charles J., Napier, Mary E., Haroon, Zishan A., Zamboni, William C., DeSimone, Joseph M.
Publicado em 2014