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Rendering Protein-Based Particles Transiently Insoluble for Therapeutic Applications

Herein we report the fabrication of protein (bovine serum albumin, BSA) particles which were rendered transiently insoluble using a novel, reductively labile disulfide-based cross-linker. After being cross-linked, the protein particles retain their integrity in aqueous solution and dissolve preferen...

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Detalhes bibliográficos
Main Authors: Xu, Jing, Wang, Jin, Luft, J. Christopher, Tian, Shaomin, Owens, Gary, Pandya, Ashish A., Berglund, Peter, Pohlhaus, Patrick, Maynor, Benjamin W., Napier, Mary E., DeSimone, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365610/
https://ncbi.nlm.nih.gov/pubmed/22568387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302363r
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