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Incorporation and Controlled Release of Silyl Ether Prodrugs from PRINT Nanoparticles
Asymmetric bifunctional silyl ether (ABS) prodrugs of chemotherapeutics were synthesized and incorporated within 200 nm x 200 nm particles. ABS prodrugs of gemcitabine were selected as model compounds because of the difficulty to encapsulate a water soluble drug within a hydrogel. The resulting drug...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362319/ https://ncbi.nlm.nih.gov/pubmed/22545784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301710z |
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