Functional STAT3 deficiency compromises the generation of human T follicular helper cells

T follicular helper (Tfh) cells are critical for providing the necessary signals to induce differentiation of B cells into memory and Ab-secreting cells. Accordingly, it is important to identify the molecular requirements for Tfh cell development and function. We previously found that IL-12 mediates...

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Main Authors: Ma, Cindy S., Avery, Danielle T., Chan, Anna, Batten, Marcel, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Arkwright, Peter D., Kreins, Alexandra Y., Averbuch, Diana, Engelhard, Dan, Magdorf, Klaus, Kilic, Sara S., Minegishi, Yoshiyuki, Nonoyama, Shigeaki, French, Martyn A., Choo, Sharon, Smart, Joanne M., Peake, Jane, Wong, Melanie, Gray, Paul, Cook, Matthew C., Fulcher, David A., Casanova, Jean-Laurent, Deenick, Elissa K., Tangye, Stuart G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2012
Ábhair:
Immunobiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355712/
https://ncbi.nlm.nih.gov/pubmed/22403255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-392985
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