Functional STAT3 deficiency compromises the generation of human T follicular helper cells

T follicular helper (Tfh) cells are critical for providing the necessary signals to induce differentiation of B cells into memory and Ab-secreting cells. Accordingly, it is important to identify the molecular requirements for Tfh cell development and function. We previously found that IL-12 mediates...

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Główni autorzy: Ma, Cindy S., Avery, Danielle T., Chan, Anna, Batten, Marcel, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Arkwright, Peter D., Kreins, Alexandra Y., Averbuch, Diana, Engelhard, Dan, Magdorf, Klaus, Kilic, Sara S., Minegishi, Yoshiyuki, Nonoyama, Shigeaki, French, Martyn A., Choo, Sharon, Smart, Joanne M., Peake, Jane, Wong, Melanie, Gray, Paul, Cook, Matthew C., Fulcher, David A., Casanova, Jean-Laurent, Deenick, Elissa K., Tangye, Stuart G.
Format: Artigo
Język:Inglês
Wydane: American Society of Hematology 2012
Hasła przedmiotowe:
Immunobiology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355712/
https://ncbi.nlm.nih.gov/pubmed/22403255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-392985
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