Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells

p66Shc, a longevity adaptor protein, is demonstrated as a key regulator of reactive oxygen species (ROS) metabolism involved in aging and cardiovascular diseases. Vascular endothelial growth factor (VEGF) stimulates endothelial cell (EC) migration and proliferation primarily through the VEGF recepto...

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Detaylı Bibliyografya
Asıl Yazarlar: Oshikawa, Jin, Kim, Seok-Jo, Furuta, Eiji, Caliceti, Cristiana, Chen, Gin-Fu, McKinney, Ronald D., Kuhr, Frank, Levitan, Irena, Fukai, Tohru, Ushio-Fukai, Masuko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Signaling and Stress Response
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353779/
https://ncbi.nlm.nih.gov/pubmed/22101521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00739.2011
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