IQGAP1 Is Involved in Post-Ischemic Neovascularization by Regulating Angiogenesis and Macrophage Infiltration

BACKGROUND: Neovascularization is an important repair mechanism in response to ischemic injury and is dependent on inflammation, angiogenesis and reactive oxygen species (ROS). IQGAP1, an actin-binding scaffold protein, is a key regulator for actin cytoskeleton and motility. We previously demonstrat...

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Autors principals: Urao, Norifumi, Razvi, Masooma, Oshikawa, Jin, McKinney, Ronald D., Chavda, Rupal, Bahou, Wadie F., Fukai, Tohru, Ushio-Fukai, Masuko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955540/
https://ncbi.nlm.nih.gov/pubmed/20976168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013440
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