Localized Cysteine Sulfenic Acid Formation by Vascular Endothelial Growth Factor: Role in Endothelial Cell Migration and Angiogenesis

Reactive oxygen species (ROS) are important mediators for VEGF receptor 2 (VEGFR2) signaling involved in angiogenesis. The initial product of Cys oxidation, Cysteine sulfenic acid (Cys-OH), is a key intermediate in redox signal transduction; however, its role in VEGF signaling is unknown. We previou...

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Detalhes bibliográficos
Main Authors: Kaplan, Nihal, Urao, Norifumi, Furuta, Eiji, Kim, Seok-Jo, Razvi, Masooma, Nakamura, Yoshimasa, McKinney, Ronald D., Poole, Leslie B, Fukai, Tohru, Ushio-Fukai, Masuko
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685280/
https://ncbi.nlm.nih.gov/pubmed/21740309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2011.602073
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