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ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis

Reactive oxygen species (ROS) derived from NADPH oxidase (NOX) and mitochondria play a critical role in growth factor-induced switch from a quiescent to an angiogenic phenotype in endothelial cells (ECs). However, how highly diffusible ROS produced from different sources can coordinate to stimulate...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Kim, Young-Mee, Kim, Seok-Jo, Tatsunami, Ryosuke, Yamamura, Hisao, Fukai, Tohru, Ushio-Fukai, Masuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494593/
https://ncbi.nlm.nih.gov/pubmed/28424170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00346.2016
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