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2-Hydroxyestradiol slows progression of experimental polycystic kidney disease
Male gender is a risk factor for progression of polycystic kidney disease (PKD). 17β-Estradiol (E2) protects experimentally, but clinical use is limited by adverse effects. Novel E2 metabolites provide many benefits of E2 without stimulating the estrogen receptor, and thus may be safer. We hypothesi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353649/ https://ncbi.nlm.nih.gov/pubmed/22160773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00265.2011 |
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