Загрузка...
Folate-Conjugated Rapamycin Slows Progression of Polycystic Kidney Disease
Activation of the mammalian target of rapamycin (mTOR) signaling pathway is aberrant in autosomal-dominant polycystic kidney disease (ADPKD). The mTOR inhibitors, such as rapamycin, ameliorate PKD in rodent models, but clinical trials have not shown benefit, possibly as a result of low tissue concen...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458469/ https://ncbi.nlm.nih.gov/pubmed/22859856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012040367 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|