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2-Hydroxyestradiol slows progression of experimental polycystic kidney disease

Male gender is a risk factor for progression of polycystic kidney disease (PKD). 17β-Estradiol (E2) protects experimentally, but clinical use is limited by adverse effects. Novel E2 metabolites provide many benefits of E2 without stimulating the estrogen receptor, and thus may be safer. We hypothesi...

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Detalhes bibliográficos
Main Authors: Anderson, Sharon, Oyama, Terry T., Lindsley, Jessie N., Schutzer, William E., Beard, Douglas R., Gattone, Vincent H., Komers, Radko
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353649/
https://ncbi.nlm.nih.gov/pubmed/22160773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00265.2011
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