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Effects of xanthine oxidase inhibition with febuxostat on the development of nephropathy in experimental type 2 diabetes
BACKGROUND AND PURPOSE: Elevated serum uric acid (UA) is a risk factor for the development of kidney disease. Inhibitors of xanthine oxidase (XOi), an enzyme involved in UA synthesis, have protective effects at early stages of experimental diabetic nephropathy (DN). However, long‐term effects of XOi...
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| Vydáno v: | Br J Pharmacol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978156/ https://ncbi.nlm.nih.gov/pubmed/27238746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13527 |
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