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Effects of xanthine oxidase inhibition with febuxostat on the development of nephropathy in experimental type 2 diabetes

BACKGROUND AND PURPOSE: Elevated serum uric acid (UA) is a risk factor for the development of kidney disease. Inhibitors of xanthine oxidase (XOi), an enzyme involved in UA synthesis, have protective effects at early stages of experimental diabetic nephropathy (DN). However, long‐term effects of XOi...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Komers, Radko, Xu, Bei, Schneider, Jennifer, Oyama, Terry T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978156/
https://ncbi.nlm.nih.gov/pubmed/27238746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13527
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