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WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway
WNK [with no lysine (K)] kinase is a subfamily of serine/threonine kinases. Mutations in two members of this family (WNK1 and WNK4) cause pseudohypoaldosteronism type II featuring hypertension, hyperkalemia, and metabolic acidosis. WNK1 and WNK4 were shown to regulate sodium chloride cotransporter (...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353643/ https://ncbi.nlm.nih.gov/pubmed/22114204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00032.2011 |
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