Aldosterone modulates thiazide-sensitive sodium chloride cotransporter abundance via DUSP6-mediated ERK1/2 signaling pathway

Thiazide-sensitive sodium chloride cotransporter (NCC) plays an important role in maintaining blood pressure. Aldosterone is known to modulate NCC abundance. Previous studies reported that dietary salts modulated NCC abundance through either WNK4 [with no lysine (k) kinase 4]-SPAK (Ste20-related pro...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Feng, Xiuyan, Zhang, Yiqian, Shao, Ningjun, Wang, Yanhui, Zhuang, Zhizhi, Wu, Ping, Lee, Matthew J., Liu, Yingli, Wang, Xiaonan, Zhuang, Jieqiu, Delpire, Eric, Gu, Dingying, Cai, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437001/
https://ncbi.nlm.nih.gov/pubmed/25761881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00543.2014
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