WNK1 Activates Large-Conductance Ca(2+)-Activated K(+) Channels through Modulation of ERK1/2 Signaling

With no lysine (WNK) kinases are members of the serine/threonine kinase family. We previously showed that WNK4 inhibits renal large-conductance Ca(2+)-activated K(+) (BK) channel activity by enhancing its degradation through a lysosomal pathway. In this study, we investigated the effect of WNK1 on B...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Liu, Yingli, Song, Xiang, Shi, Yanling, Shi, Zhen, Niu, Weihui, Feng, Xiuyan, Gu, Dingying, Bao, Hui-Fang, Ma, He-Ping, Eaton, Douglas C., Zhuang, Jieqiu, Cai, Hui
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2015
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378107/
https://ncbi.nlm.nih.gov/pubmed/25145935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014020186
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