Single-Domain Antibody-SH3 Fusions for Efficient Neutralization of HIV-1 Nef Functions

HIV-1 Nef is essential for AIDS pathogenesis, but this viral protein is not targeted by antiviral strategies. The functions of Nef are largely related to perturbations of intracellular trafficking and signaling pathways through leucine-based and polyproline motifs that are required for interactions...

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Autores principales: Bouchet, Jérôme, Hérate, Cécile, Guenzel, Carolin A., Vérollet, Christel, Järviluoma, Annika, Mazzolini, Julie, Rafie, Salomeh, Chames, Patrick, Baty, Daniel, Saksela, Kalle, Niedergang, Florence, Maridonneau-Parini, Isabelle, Benichou, Serge
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347381/
https://ncbi.nlm.nih.gov/pubmed/22345475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06329-11
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