Single-Domain Antibody-SH3 Fusions for Efficient Neutralization of HIV-1 Nef Functions

HIV-1 Nef is essential for AIDS pathogenesis, but this viral protein is not targeted by antiviral strategies. The functions of Nef are largely related to perturbations of intracellular trafficking and signaling pathways through leucine-based and polyproline motifs that are required for interactions...

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Bibliografiska uppgifter
Huvudupphovsmän: Bouchet, Jérôme, Hérate, Cécile, Guenzel, Carolin A., Vérollet, Christel, Järviluoma, Annika, Mazzolini, Julie, Rafie, Salomeh, Chames, Patrick, Baty, Daniel, Saksela, Kalle, Niedergang, Florence, Maridonneau-Parini, Isabelle, Benichou, Serge
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347381/
https://ncbi.nlm.nih.gov/pubmed/22345475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06329-11
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