Single-Domain Antibody-SH3 Fusions for Efficient Neutralization of HIV-1 Nef Functions

HIV-1 Nef is essential for AIDS pathogenesis, but this viral protein is not targeted by antiviral strategies. The functions of Nef are largely related to perturbations of intracellular trafficking and signaling pathways through leucine-based and polyproline motifs that are required for interactions...

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Bibliografiske detaljer
Main Authors: Bouchet, Jérôme, Hérate, Cécile, Guenzel, Carolin A., Vérollet, Christel, Järviluoma, Annika, Mazzolini, Julie, Rafie, Salomeh, Chames, Patrick, Baty, Daniel, Saksela, Kalle, Niedergang, Florence, Maridonneau-Parini, Isabelle, Benichou, Serge
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347381/
https://ncbi.nlm.nih.gov/pubmed/22345475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06329-11
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