Single-Domain Antibody-SH3 Fusions for Efficient Neutralization of HIV-1 Nef Functions

HIV-1 Nef is essential for AIDS pathogenesis, but this viral protein is not targeted by antiviral strategies. The functions of Nef are largely related to perturbations of intracellular trafficking and signaling pathways through leucine-based and polyproline motifs that are required for interactions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bouchet, Jérôme, Hérate, Cécile, Guenzel, Carolin A., Vérollet, Christel, Järviluoma, Annika, Mazzolini, Julie, Rafie, Salomeh, Chames, Patrick, Baty, Daniel, Saksela, Kalle, Niedergang, Florence, Maridonneau-Parini, Isabelle, Benichou, Serge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347381/
https://ncbi.nlm.nih.gov/pubmed/22345475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06329-11
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