α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered Monomer

Since the discovery and isolation of α-synuclein (α-syn) from human brains, it has been widely accepted that it exists as an intrinsically disordered monomeric protein. Two recent studies suggested that α-syn produced in Escherichia coli or isolated from mammalian cells and red blood cells exists pr...

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Dettagli Bibliografici
Autori principali: Fauvet, Bruno, Mbefo, Martial K., Fares, Mohamed-Bilal, Desobry, Carole, Michael, Sarah, Ardah, Mustafa T., Tsika, Elpida, Coune, Philippe, Prudent, Michel, Lion, Niels, Eliezer, David, Moore, Darren J., Schneider, Bernard, Aebischer, Patrick, El-Agnaf, Omar M., Masliah, Eliezer, Lashuel, Hilal A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346117/
https://ncbi.nlm.nih.gov/pubmed/22315227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318949
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