Loading...

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease

Lewy bodies (LBs) are intraneuronal inclusions consisting primarily of fibrillized human α-synuclein (hα-Syn) protein, which represent the major pathological hallmark of Parkinson's disease (PD). Although doubling hα-Syn expression provokes LB pathology in humans, hα-Syn overexpression does not...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Fares, Mohamed-Bilal, Maco, Bohumil, Oueslati, Abid, Rockenstein, Edward, Ninkina, Natalia, Buchman, Vladimir L., Masliah, Eliezer, Lashuel, Hilal A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763739/
https://ncbi.nlm.nih.gov/pubmed/26839406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512876113
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!