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The many faces of α-synuclein: from structure and toxicity to therapeutic target

Disorders characterized by α-synuclein (α-syn) accumulation, Lewy body formation and parkinsonism (and in some cases dementia) are collectively known as Lewy body diseases. The molecular mechanism(s) through which α-syn abnormally accumulates and contributes to neurodegeneration in these disorders r...

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Bibliographic Details
Published in:Nat Rev Neurosci
Main Authors: Lashuel, Hilal A., Overk, Cassia R., Oueslati, Abid, Masliah, Eliezer
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295774/
https://ncbi.nlm.nih.gov/pubmed/23254192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3406
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