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The many faces of α-synuclein: from structure and toxicity to therapeutic target
Disorders characterized by α-synuclein (α-syn) accumulation, Lewy body formation and parkinsonism (and in some cases dementia) are collectively known as Lewy body diseases. The molecular mechanism(s) through which α-syn abnormally accumulates and contributes to neurodegeneration in these disorders r...
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| Опубликовано в: : | Nat Rev Neurosci |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295774/ https://ncbi.nlm.nih.gov/pubmed/23254192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3406 |
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