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Phosphorylation of α-Synuclein at Y125 and S129 Alters Its Metal Binding Properties: Implications for Understanding the Role of α-Synuclein in the Pathogenesis of Parkinson’s Disease and Related Disorders
[Image: see text] α-Synuclein (α-syn) is a 140-amino acid protein that plays a central role in the pathogenesis of Parkinson’s disease (PD) and other synucleinopathies. However, the molecular determinants that are responsible for triggering and/or propagating α-syn aggregation and toxicity remain po...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2011
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369716/ https://ncbi.nlm.nih.gov/pubmed/22860160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200074d |
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