Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125

Despite increasing evidence that supports the role of different post-translational modifications (PTMs) in modulating α-synuclein (α-syn) aggregation and toxicity, relatively little is known about the functional consequences of each modification and whether or not these modifications are regulated b...

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Main Authors: Hejjaoui, Mirva, Butterfield, Sara, Fauvet, Bruno, Vercruysse, Filip, Cui, Jia, Dikiy, Igor, Prudent, Michel, Olschewski, Diana, Zhang, Yan, Eliezer, David, Lashuel, Hilal A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592575/
https://ncbi.nlm.nih.gov/pubmed/22339654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210866j
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