Chargement en cours...
Semisynthetic and in vitro phosphorylation of alpha-synuclein at Y39 promotes functional partly-helical membrane-bound states resembling those induced by PD mutations
Alpha-synuclein is a presynaptic protein of poorly understood function that is linked to both genetic and sporadic forms of Parkinson’s disease. We have proposed that alpha-synuclein may function specifically at synaptic vesicles docked at the plasma membrane, and that the broken-helix state of the...
Enregistré dans:
| Publié dans: | ACS Chem Biol |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240779/ https://ncbi.nlm.nih.gov/pubmed/27356045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00539 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|