Characterization of Semisynthetic and Naturally N(α)-Acetylated α-Synuclein in Vitro and in Intact Cells: IMPLICATIONS FOR AGGREGATION AND CELLULAR PROPERTIES OF α-SYNUCLEIN

N-terminal acetylation is a very common post-translational modification, although its role in regulating protein physical properties and function remains poorly understood. α-Synuclein (α-syn), a protein that has been linked to the pathogenesis of Parkinson disease, is constitutively N(α)-acetylated...

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Detalhes bibliográficos
Main Authors: Fauvet, Bruno, Fares, Mohamed-Bilal, Samuel, Filsy, Dikiy, Igor, Tandon, Anurag, Eliezer, David, Lashuel, Hilal A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436566/
https://ncbi.nlm.nih.gov/pubmed/22718772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383711
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