Insulin inhibits hepatocyte iNOS expression induced by cytokines by an Akt-dependent mechanism

Hepatocyte inducible nitric oxide synthese (iNOS) expression is a tightly controlled pathway that mediates hepatic inflammation and hepatocyte injury in a variety of disease states. We have shown that cyclic adenosine monophosphate (cAMP) regulates cytokine-induced hepatocyte iNOS expression through...

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Autores principales: Harbrecht, Brian G., Nweze, Ikenna, Smith, Jason W., Zhang, Baochun
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
Materias:
Hormones and Signaling
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345958/
https://ncbi.nlm.nih.gov/pubmed/22038823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00114.2011
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