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Calcium-mediated signaling and calmodulin-dependent kinase regulate hepatocyte inducible nitric oxide synthase expression
BACKGROUND: Nitric oxide synthase (iNOS) is induced in hepatocytes by shock and inflammatory stimuli. Excessive NO from iNOS mediates shock-induced hepatic injury and death so understanding the regulation of iNOS will help elucidate the pathophysiology of septic shock. In vitro, cytokines induce iNO...
Enregistré dans:
| Publié dans: | J Surg Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268076/ https://ncbi.nlm.nih.gov/pubmed/25150084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2014.07.042 |
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