17β-ESTRADIOL ATTENUATES CYTOKINE-INDUCED NITRIC OXIDE PRODUCTION IN RAT HEPATOCYTE

OBJECTIVE: Nitric Oxide (NO) regulation during shock and sepsis is complex. NO production by endothelial NO synthase (eNOS) maintains microvascular perfusion and prevents shock-induced organ injury. However, overproduction of NO by inducible NO synthase (iNOS) contributes to liver dysfunction after...

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Main Authors: NWEZE, IKENNA C., SMITH, JASON W., ZHANG, BAOCHUN, LAKSHMANAN, JAGANATHAN, KLINGE, CAROLYN M., HARBRECHT, BRIAN G
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422572/
https://ncbi.nlm.nih.gov/pubmed/22846947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e31825a789b
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