Akt-Mediated Signaling is Induced by Cytokines and Cyclic Adenosine Monophosphate and Suppresses Hepatocyte Inducible Nitric Oxide Synthase Expression Independent of MAPK P44/42

Cyclic AMP inhibits the expression of nitric oxide synthase in hepatocytes but the mechanism for this effect is incompletely understood. Cyclic AMP can activate several intracellular signaling pathways in hepatocytes including Protein Kinase A (PKA), cAMP regulated guanine nucleotide exchange factor...

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Hlavní autoři: Zhang, Baochun, Li, Suping, Harbrecht, Brian G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014387/
https://ncbi.nlm.nih.gov/pubmed/20934465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.10.001
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